PNPLA3 and TM6SF2 polymorphisms in Brazilian patients with nonalcoholic fatty liver disease
نویسندگان
چکیده
منابع مشابه
Nonalcoholic Fatty Liver Disease Treatment
Nonalcoholic fatty liver disease (NAFLD) is increasing in pediatric age group parallel to the growing prevalence of obesity and overweight all around the world. So changing in life style and interventions on obesogenic environment is cornerstone of NAFLD therapy in obese children. Some experts recommend that children and adolescents be encouraged to follow a low-fat, low-glycemic-index diet t...
متن کاملNonalcoholic fatty liver disease and the PNPLA3 gene.
Nonalcoholic fatty liver disease, a potentially fatal obesity-related condition, affects more than 70 million people in the United States. Nurses are well-positioned to impact this genetically influenced disease by is increasing awareness, providing patient education, and advocating for affected persons.
متن کاملOmentin-1 rs2274907 and resistin rs1862513 polymorphisms influence genetic susceptibility to nonalcoholic fatty liver disease
Nonalcoholic fatty liver disease (NAFLD) is an obesity-associated disease and dysregulation of adipokines has an important role in its development. Omentin-1 (ITLN1 protein) and resistin are two adipokine secreted from adipose tissue. Single nucleotide polymorphisms in the adipokine genes may affect expression and activity of the adipokine, and thus play a contributory role in NAFLD pathogenesi...
متن کاملComparison of Physical Activity and Fiber and Sugar Intake in Patients with Nonalcoholic Fatty Liver Disease with Healthy Individuals
Introduction: Nutrition as a modifiable risk factor that plays an important role in prevent or delay the onset of non-alcoholic fatty liver disease (NAFLD). Thus, the aim of the current study was to assess and compare physical activity, dietary fiber and sugar intake between non-alcoholic fatty liver disease and healthy individuals.Methods: The present case-con...
متن کاملAssociation of rs738409 Polymorphism in the PNPLA3 Gene with Nonalcoholic Fatty Liver Disease
Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease and has an estimated incidence of 20%–30% in the general population and 67%–75% in the obese population. Genetic predisposition can play an important role in development of this disease. Nonsynonymous coding SNP rs738409 C/G (I148Met) in the PNPLA3 gene has been found to be associated with the presence of...
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ژورنال
عنوان ژورنال: World Journal of Hepatology
سال: 2020
ISSN: 1948-5182
DOI: 10.4254/wjh.v12.i10.792